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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRP9
All Species:
19.7
Human Site:
S174
Identified Species:
36.11
UniProt:
O43818
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43818
NP_004695.1
475
51841
S174
D
C
S
I
I
K
W
S
V
E
S
G
R
K
L
Chimpanzee
Pan troglodytes
XP_001170125
475
51836
S174
D
C
T
V
I
K
W
S
V
E
S
G
R
K
L
Rhesus Macaque
Macaca mulatta
XP_001087877
541
58617
S240
D
C
T
I
I
K
W
S
M
E
S
G
R
K
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91WM3
475
52089
S174
D
C
T
I
I
K
W
S
V
E
T
G
R
K
L
Rat
Rattus norvegicus
NP_001102248
478
52484
S177
D
C
T
I
I
K
W
S
V
E
T
G
R
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414243
454
49618
E173
D
G
S
V
I
K
W
E
V
E
S
G
K
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P5M2
305
33318
S50
L
V
K
V
W
K
W
S
D
E
K
L
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001014529
484
53267
C188
S
Q
F
L
L
K
W
C
T
E
T
G
K
V
L
Honey Bee
Apis mellifera
XP_394355
328
36323
L73
I
S
T
D
N
K
F
L
V
V
G
D
N
G
S
Nematode Worm
Caenorhab. elegans
NP_872030
518
56758
N168
E
S
S
I
V
K
F
N
V
G
T
R
K
V
V
Sea Urchin
Strong. purpuratus
XP_787944
475
52623
N173
D
C
S
I
I
K
W
N
A
A
T
G
K
K
E
Poplar Tree
Populus trichocarpa
XP_002306239
502
55779
D189
D
G
T
I
L
H
W
D
V
D
S
G
K
A
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06506
573
65036
D200
D
L
Q
L
T
K
Y
D
I
T
D
F
S
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
86.8
N.A.
N.A.
92.6
92.6
N.A.
N.A.
60
N.A.
22.1
N.A.
42.5
35.7
33.4
50.9
Protein Similarity:
100
100
87.4
N.A.
N.A.
94.9
94.5
N.A.
N.A.
73.8
N.A.
35.1
N.A.
61.3
48.2
52.5
68
P-Site Identity:
100
86.6
86.6
N.A.
N.A.
86.6
86.6
N.A.
N.A.
73.3
N.A.
26.6
N.A.
33.3
13.3
26.6
60
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
86.6
N.A.
33.3
N.A.
60
26.6
73.3
80
Percent
Protein Identity:
37.4
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
57.5
N.A.
N.A.
N.A.
45.7
N.A.
P-Site Identity:
40
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% A
% Cys:
0
47
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
70
0
0
8
0
0
0
16
8
8
8
8
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
8
0
62
0
0
8
0
16
% E
% Phe:
0
0
8
0
0
0
16
0
0
0
0
8
0
0
0
% F
% Gly:
0
16
0
0
0
0
0
0
0
8
8
70
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
54
54
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
93
0
0
0
0
8
0
39
62
0
% K
% Leu:
8
8
0
16
16
0
0
8
0
0
0
8
0
8
54
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
16
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
39
0
8
% R
% Ser:
8
16
31
0
0
0
0
47
0
0
39
0
8
0
8
% S
% Thr:
0
0
47
0
8
0
0
0
8
8
39
0
0
0
0
% T
% Val:
0
8
0
24
8
0
0
0
62
8
0
0
0
16
8
% V
% Trp:
0
0
0
0
8
0
77
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _